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Sildenafil citrate 100 mg starting dose in men with erectile dysfunction in an international, double-blind, placebo-controlled study: effect on the sexual experience and reducing feelings of anxiety about the next intercourse attempt

Sildenafil > sildenafil citrate 100 mg


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug are: Sildenafil can cause a serious drop in your blood pressure when used with nitrates. A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke.

Ethics declarations

In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a person get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Using an effective barrier method (latex or polyurethane condom/dental dams) during sexual activity will help to decrease your risk of infection. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

Corresponding author

Sildenafil is also available in other brands and strengths for high blood pressure in the lungs (pulmonary hypertension). Read the Patient Information Leaflet if available from your pharmacist before you start taking sildenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist. To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before works best). Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide) recreational drugs called "poppers" containing amyl or butyl nitrite If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure.

  • People with heart problems should consult a doctor before using sildenafil 100 mg.
  • Sildenafil is contraindicated in patients with severe liver or kidney impairment.
  • Allergic reactions, though rare, may include rash, itching, or swelling.

Other medications can affect the removal of sildenafil from your body, which may affect how sildenafil works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), mifepristone, rifampin, ritonavir, among others. Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911.

  • Sildenafil citrate 100 mg is a medication primarily used to treat erectile dysfunction.
  • The typical recommended dose of sildenafil citrate is 50 to 100 mg.
  • It works by increasing blood flow to the penis for improved erections.

Otherwise, call a poison control center right away.

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US residents can call 1-800-222-1222.

What other information should I know?

Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, sildenafil should be used only when clearly needed. Since high blood pressure in the lungs is a serious condition that can harm both a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, discuss with sildenafil pick up your doctor right away the benefits and risks of using this medication during pregnancy. Canada residents can call 1-844-764-7669. Symptoms of overdose may include: severe dizziness, fainting, painful/prolonged erection.

  • Sildenafil 100 mg is not a cure for erectile dysfunction but helps temporarily.
  • Lifestyle changes like exercise and diet can enhance treatment effectiveness.
  • Open communication with a partner can improve the sexual experience and treatment satisfaction.

Do not share this medication with others.

Usual Adult Dose for Pulmonary Hypertension

Many people using this medication do not have serious side effects. Sexual activity may put extra strain on your heart, especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex, stop and get medical help right away: Rarely, sudden decreased vision, or even permanent blindness, may occur in one or both eyes (NAION). If this serious problem occurs, stop taking sildenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke.

Regional issues

Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking sildenafil and get medical help right away if these effects occur. Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. A very serious allergic reaction to this drug is rare. Store at room temperature away from light and moisture. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

Other Comments

This medication may take longer to start working if you take it with a high-fat meal. Do not take more than once daily as needed. The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if your condition does not get better.

Platelet-aggregation Inhibitors

Dizziness, headache, flushing, or stomach upset may occur. Vision sildenafil oral jelly 100mg lovegra changes such as increased sensitivity to light, blurred vision, or trouble telling blue and green colors apart may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Properly discard this product when it is expired or no longer needed.

Contraindication Reason Alternatives
Concurrent Nitrate Use Risk of severe hypotension Use other ED treatments
Cardiovascular Instability May exacerbate underlying conditions Consult cardiologist
Hypersensitivity Reactions Allergic response Discontinue use
Severe Liver Impairment Altered drug metabolism Lower dose or avoid

Consult your pharmacist or local waste disposal company.

  • Sildenafil 100 mg can be used for pulmonary arterial hypertension in some cases.
  • It is not intended for use in women or children.
  • Regular use of sildenafil does not cure erectile dysfunction but manages symptoms.

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product.

Other uses for this medicine

Unless explicitly stated in writing, no direct affiliation, sponsorship, or endorsement by individual product manufacturers with Premium Rx National, LLC should be implied. All brand names, trade names, and trademarks are the property of their respective owners and are presented solely for accurate product identification and informational reference. Sildenafil Citrate 100 mg / 1 Tablet is tracked under NDC 80425-0503-02 and rolls up into product family 80425-0503. Use this page to review package-level identifiers before comparing related family pages or starting a quote review. Click a tag to refine the catalog view around this product reference.

Therapies for Erectile Dysfunction

Use official labeling and directory references to confirm presentation details while your team reviews the PRN catalog entry and related sourcing paths. These nearby package-level pages can help healthcare teams compare related packaging or presentation differences inside the same product-NDC family. Sildenafil Citrate 100 mg / 1 Tablet 60 Tablet, NDC 80425-0503-02, is a Advanced Rx of Tennessee, LLC 100 mg / 1 tablet presentation packaged as 60 Tablet. Possible 10-digit display formats: 80425-503-02 (8042550302), 80425-0503-2 (8042505032) Multiple 10-digit display-format aliases can map to the same stored 11-digit billing NDC, so these are shown as search aliases rather than a single asserted package format. Other package sizes in this family: 30 Tablet, 90 Tablet Compare related presentations: Sildenafil Citrate 100 mg / 1 Tablet 30 Tablet, Sildenafil Citrate 100 mg / 1 Tablet 90 Tablet Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). This information does not assure that this product is safe, effective, or appropriate for you.

2.4 Dosage Adjustments Due to Drug Interactions

This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure) penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease) conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma) eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION) This drug may make you dizzy or cause vision problems. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. This information is not individual medical advice and does not substitute for the advice of your health care professional.

What happens if I miss a dose?

However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat) This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. You may report side effects to FDA at 1-800-FDA-1088 or at In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Always ask your health care professional for complete information about this product and your specific health needs. Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019.

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