have an eye problem called retinitis pigmentosa have ever had sudden loss of vision in one or both eyes, including an eye problem called non-arteritic anterior ischemic optic neuropathy (NAION) have ever had hearing problems such as ringing in the ears, dizziness, or loss of hearing have a deformed penis shape or Peyronie’s disease have any blood cell problems such as sickle cell anemia are pregnant or plan to become pregnant. It is not known if sildenafil for oral suspension will harm your unborn baby. Talk with your healthcare provider about the best way to feed your baby during treatment with sildenafil for oral suspension.
| Region | Estimated Market Size (2023) | Growth Rate | Key Players | Typical Uses Scope |
|---|---|---|---|---|
| North America | $150 million | 5% annually | Pfizer, Cipla, Teva | ED, pulmonary hypertension |
| Europe | $100 million | 4.5% annually | Bayer, Sun Pharma | Pulmonary hypertension, off-label uses |
| Asia-Pacific | $200 million | 7% annually | Cipla, Aurobindo, Zydus | Broader use, pediatric cases |
| Rest of World | $50 million | 3.5% annually | Various local manufacturers | Growing awareness and approval |
Tell your healthcare provider about all of the medicines you or your child take, including prescription and overthe-counter medicines, vitamins, and herbal supplements. Sildenafil for oral suspension and certain other medicines may affect each other and can cause side effects.
5.2 Worsening Pulmonary Vascular Occlusive Disease
If you are giving sildenafil oral suspension to a child, make sure they are in an upright position before giving the medicine. See full prescribing information for SILDENAFIL FOR ORAL SUSPENSION. SILDENAFIL for oral suspension Initial U.S. Approval: 1998RECENT MAJOR CHANGESIndications and Usage (1) 1/2023Dosage and Administration (2.1, 2.2, 2.3) 1/2023INDICATIONS AND USAGEAdultsSildenafil for oral suspension is a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. (1) (1)DOSAGE AND ADMINISTRATIONAdults: 20 mg three times a day Dose may be increased based on symptoms and tolerability.
What’s the difference between sildenafil and Viagra?
(2.1)DOSAGE FORMS AND STRENGTHSFor oral suspension: 10 mg/mL (when reconstituted) (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil for oral suspension may cause serious vaso-occlusive crises. (5.6)Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil) product. (7)See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 1/2024 Adults: 20 mg three times a day Dose may be increased based on symptoms and tolerability. Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil for oral suspension may cause serious vaso-occlusive crises. See “What is the most important information I should know about sildenafil for oral suspension?” Sildenafil for oral suspension contains sildenafil, which is the same medicine found in another medicine called VIAGRA®. Do not take VIAGRA or other PDE-5 inhibitors during treatment with sildenafil for oral suspension. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure. Know the medicines you or your child take. Keep a list of your or your child’s medicines and show it to your healthcare provider and pharmacist when you get a new medicine. Take or give sildenafil for oral suspension exactly as your healthcare provider tells you. Your healthcare provider may change your or your child’s dose of sildenafil for oral suspension as needed. Do not change your dose or stop taking sildenafil for oral suspension without talking to your healthcare provider. Sildenafil for oral suspension may be prescribed to you as sildenafil oral suspension.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra | 100mg | 12 Pills | 55.64€ 52.99€ | |
| Kamagra | 100mg | 20 Pills | 86.09€ 81.99€ | |
| Viagra Generic | 150mg | 20 Pills | 55.02€ 52.40€ | |
| Viagra Generic | 50mg | 270 + 8 Pills | 198.48€ 189.03€ | |
| Viagra Generic | 25mg | 120 + 6 Pills | 125.56€ 119.58€ | |
| Kamagra Polo | 100mg | 84 + 4 Pills | 244.49€ 232.85€ | |
| Kamagra Oral Jelly | 100mg | 30 + 5 Sachets | 136.20€ 129.71€ | |
| Viagra Generic | 25mg | 90 + 6 Pills | 105.03€ 100.03€ | |
| Viagra Generic | 25mg | 270 + 8 Pills | 184.26€ 175.49€ | |
| Viagra Generic | 150mg | 30 + 2 Pills | 72.32€ 68.88€ | |
| Viagra Generic | 50mg | 10 Pills | 26.87€ 25.59€ | |
| Viagra Generic | 50mg | 30 + 4 Pills | 54.26€ 51.68€ | |
| Kamagra | 100mg | 360 + 6 Pills | 839.95€ 799.95€ | |
| Kamagra Polo | 100mg | 180 + 8 Pills | 446.52€ 425.26€ | |
| Viagra Generic | 50mg | 20 Pills | 40.52€ 38.59€ |
Take your prescribed dose of sildenafil oral suspension 3 times a day. See the detailed Instructions for Use that comes with sildenafil oral suspension for information on how to take or give sildenafil oral suspension. Do not mix sildenafil oral suspension with other medicine or flavoring.
- Sildenafil syrup may be preferred for those with swallowing issues.
- It can be mixed with water or other liquids if approved by a doctor.
- The taste of the syrup might require flavoring agents.
- There's limited data on the stability of sildenafil syrup long-term.
- Use of sildenafil in women is not approved and not well-studied.
If you or your child take too much sildenafil for oral suspension call your healthcare provider or go to the nearest hospital emergency room right away. Sildenafil for oral suspension may cause serious side effects, including: See “What is the most important information I should know about sildenafil for oral suspension?” Sildenafil for oral suspension may cause low blood pressure that last for a short time. If you take medicines to treat high blood pressure, your healthcare provider should monitor your blood pressure during treatment with sildenafil for oral suspension. Decreased eyesight or permanent loss of vision in one or both eyes can be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). If you notice a sudden decrease or loss of vision in one or both eyes during treatment with sildenafil for oral suspension, contact your healthcare provider right away. Sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness. If you notice a sudden decrease or loss of hearing during treatment with sildenafil for oral suspension, contact your healthcare provider right away.
- The shelf life of sildenafil syrup depends on formulation and storage.
- Expiry dates should always be checked before use.
- Improper storage can lead to degradation of active ingredients.
- The liquid form allows for precise dose adjustments.
- Careful titration is essential to avoid overdose risks.
In men, an erection that lasts for more than 4 hours (priapism). A painful erection that lasts more than 6 hours must be treated right away or you can have lasting damage to your penis, including the inability to have erections.
In case of emergency/overdose
See the detailed Instructions for Use that comes with sildenafil oral suspension for information on how to take or give sildenafil oral suspension. Do not mix sildenafil oral suspension with other medicine or flavoring. If you or your child take too much sildenafil for oral suspension call your healthcare provider or go to the nearest hospital emergency room right away. Sildenafil for oral suspension may cause serious side effects, including: See “What is the most important information I should know about sildenafil for oral suspension?” Sildenafil for oral suspension may cause low blood pressure that last for a short time. If you take medicines to treat high blood pressure, your healthcare provider should monitor your blood pressure during treatment with sildenafil for oral suspension.
Drugs you should not use with sildenafil
Decreased eyesight or permanent loss of vision in one or both eyes can be a sign of non-arteritic anterior ischemic optic neuropathy (NAION). If you notice a sudden decrease or loss of vision in one or both eyes during treatment with sildenafil for oral suspension, contact your healthcare provider right away. Sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness. If you notice a sudden decrease or loss of hearing during treatment with sildenafil for oral suspension, contact your healthcare provider right away. In men, an erection that lasts for more than 4 hours (priapism).
8.4 Pediatric Use
A painful erection that lasts more than 6 hours must be treated right away or you can have lasting damage to your penis, including the inability to have erections. The most common side effects of sildenafil for oral suspension in adults include: The most common side effect of sildenafil for oral suspension in children is an erection that lasts sildenafil spray for more than 4 hours (priapism). General information about the safe and effective use of sildenafil for oral suspension. Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. You can ask your healthcare provider or pharmacist for information about sildenafil for oral suspension that is written for health professionals. The most common side effects of sildenafil for oral suspension in adults include: The most common side effect of sildenafil for oral suspension in children is an erection that lasts sildenafil spray for more than 4 hours (priapism). General information about the safe and effective use of sildenafil for oral suspension. Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. You can ask your healthcare provider or pharmacist for information about sildenafil for oral suspension that is written for health professionals. For more information, call 1-877-272-7901.
Mechanism of action
1 INDICATIONS AND USAGE AdultsSildenafil for Oral Suspension is indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil) product. 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage in AdultsOral DosageThe recommended dosage of Sildenafil for Oral Suspension is 20 mg three times a day. [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil) product. However, due to Viatris Specialty LLC's marketing exclusivity rights, this drug product is not labeled with that information.2.3 Reconstitution of the Powder for Oral SuspensionNote: Reconstitute the contents of the bottle with a total volume of 92 mL (60 mL followed by 32 mL). 3 DOSAGE FORMS AND STRENGTHS Sildenafil for Oral SuspensionWhite to off-white powders containing 1.60 g of sildenafil citrate (equivalent to 1.14 g of sildenafil) in a bottle for reconstitution. INSTRUCTIONS FOR USE Sildenafil (sil den′ a fil) oral suspensionRead this Instructions for Use before you start taking sildenafil oral suspension or giving sildenafil oral suspension to your child and each time you get a refill.
- Sildenafil interacts with alpha-blockers, leading to hypotension.
- The syrup should be measured with a proper dosing device.
- The syrup form is less common and might have inconsistent absorption.
- Researchers are exploring alternative delivery methods like liquids.
- Pharmaceutical companies rarely produce sildenafil syrup commercially.
This information does not take the place of talking to your healthcare provider about your or your child’s medical condition or treatment.Important information:Ask your healthcare provider or pharmacist to show you how to measure and take or give your child’s prescribed dose of sildenafil oral suspension.Your pharmacist will mix (reconstitute) sildenafil oral suspension before it is given to you. If the bottle adaptor is not in the bottle, contact your pharmacist.· Sildenafil for oral suspension should not be mixed with any other medicine or flavoring.Supplies you will need to take or give a dose of sildenafil for oral suspension (See Figure A):· 1 bottle of sildenafil for oral suspension with pre- inserted bottle adaptor· 1 oral dosing syringe (provided in the carton)Step 1.
| Aspect | Sildenafil Syrup | Sildenafil Tablets |
|---|---|---|
| Ease of administration | Easy for children or those swallowing difficulties | Convenient for most adults |
| Dosage flexibility | Precise dosage adjustments possible | Fixed doses, less flexible |
| Onset of action | Usually quicker due to liquid form | Similar, around 30–60 min |
| Bioavailability | Slightly higher (due to faster absorption) | Slightly lower |
| Storage requirements | Same storage conditions | Same storage conditions |
(See Figure E)If your child’s dose of sildenafil oral suspension is 1 mL (10 mg), measure 0.5 mL two times for a total of 1 mL of sildenafil oral suspension.If your or your child’s dose of sildenafil oral suspension is more than 2 mL (20 mg), you will need to divide the dose. Put the tip of the oral dosing syringe into your or your child’s mouth and point it towards the inside of the cheek. (See Figure G)If you are giving sildenafil oral suspension to a child, make sure they are in an upright position before giving the medicine.Step 7. Store the oral dosing syringe with the sildenafil oral suspension bottle.How should I store sildenafil for oral suspension?Store mixed (reconstituted) sildenafil for oral suspension below 86°F (30°C) or in a refrigerator between 36°F to 46°F (2°C to 8°C).Do not freeze mixed sildenafil for oral suspension.Throw away (discard) any remaining sildenafil oral suspension 60 days after mixed by the pharmacist. See the “Discard after” date written on the bottle label.Keep sildenafil for oral suspension and all medicines out of the reach of children.Manufactured by:Alkem Laboratories Ltd.,INDIA.Distributed by:Ascend Laboratories, LLCParsippany, NJ 07054This Instruction for Use has been approved by the U.S. Food and Drug Administration.Revised: July, 2023 Sildenafil (sil den′ a fil) oral suspension Read this Instructions for Use before you start taking sildenafil oral suspension or giving sildenafil oral suspension to your child and each time you get a refill. Ask your healthcare provider or pharmacist to show you how to measure and take or give your child’s prescribed dose of sildenafil oral suspension.
What are some other side effects of Sildenafil Oral Suspension?
For more information, call 1-877-272-7901. INSTRUCTIONS FOR USE Sildenafil (sil den′ a fil) oral suspensionRead this Instructions for Use before you start taking sildenafil oral suspension or giving sildenafil oral suspension to your child and each time you get a refill. This information does not take the place of talking to your healthcare provider about your or your child’s medical condition or treatment.Important information:Ask your healthcare provider or pharmacist to show you how to measure and take or give your child’s prescribed dose of sildenafil oral suspension.Your pharmacist will mix (reconstitute) sildenafil oral suspension before it is given to you. If the bottle adaptor is not in the bottle, contact your pharmacist.· Sildenafil for oral suspension should not be mixed with any other medicine or flavoring.Supplies you will need to take or give a dose of sildenafil for oral suspension (See Figure A):· 1 bottle of sildenafil for oral suspension with pre- inserted bottle adaptor· 1 oral dosing syringe (provided in the carton)Step 1. (See Figure E)If your child’s dose of sildenafil oral suspension is 1 mL (10 mg), measure 0.5 mL two times for a total of 1 mL of sildenafil oral suspension.If your or your child’s dose of sildenafil oral suspension is more than 2 mL (20 mg), you will need to divide the dose.
Who should not take sildenafil?
Put the tip of the oral dosing syringe into your or your child’s mouth and point it towards the inside of the cheek. (See Figure G)If you are giving sildenafil oral suspension to a child, make sure they are in an upright position before giving the medicine.Step 7. Store the oral dosing syringe with the sildenafil oral suspension bottle.How should I store sildenafil for oral suspension?Store mixed (reconstituted) sildenafil for oral suspension below 86°F (30°C) or in a refrigerator between 36°F to 46°F (2°C to 8°C).Do not freeze mixed sildenafil for oral suspension.Throw away (discard) any remaining sildenafil oral suspension 60 days after mixed by the pharmacist. See the “Discard after” date written on the bottle label.Keep sildenafil for oral suspension and all medicines out of the reach of children.Manufactured by:Alkem Laboratories Ltd.,INDIA.Distributed by:Ascend Laboratories, LLCParsippany, NJ 07054This Instruction for Use has been approved by the U.S. Food and Drug Administration.Revised: July, 2023 Sildenafil (sil den′ a fil) oral suspension Read this Instructions for Use before you start taking sildenafil oral suspension or giving sildenafil oral suspension to your child and each time you get a refill.
12.1 Sildenafil Oral Suspension Mechanism of Action
Ask your healthcare provider or pharmacist to show you how to measure and take or give your child’s prescribed dose of sildenafil oral suspension. · Sildenafil for oral suspension should not be mixed canada sildenafil with any other medicine or flavoring. Supplies you will need to take or give a dose of sildenafil for oral suspension (See Figure A): · 1 bottle of sildenafil for oral suspension with pre- inserted bottle adaptor · 1 oral dosing syringe (provided in the carton) Shake the bottle of sildenafil for oral suspension for 10 seconds before each use. If your child’s dose of sildenafil oral suspension is 1 mL (10 mg), measure 0.5 mL two times for a total of 1 mL of sildenafil oral suspension. If your or your child’s dose of sildenafil oral suspension is more than 2 mL (20 mg), you will need to divide the dose. · Sildenafil for oral suspension should not be mixed canada sildenafil with any other medicine or flavoring. Supplies you will need to take or give a dose of sildenafil for oral suspension (See Figure A): · 1 bottle of sildenafil for oral suspension with pre- inserted bottle adaptor · 1 oral dosing syringe (provided in the carton) Shake the bottle of sildenafil for oral suspension for 10 seconds before each use. If your child’s dose of sildenafil oral suspension is 1 mL (10 mg), measure 0.5 mL two times for a total of 1 mL of sildenafil oral suspension. If your or your child’s dose of sildenafil oral suspension is more than 2 mL (20 mg), you will need to divide the dose. If you are giving sildenafil oral suspension to a child, make sure they are in an upright position before giving the medicine. See full prescribing information for SILDENAFIL FOR ORAL SUSPENSION. SILDENAFIL for oral suspension Initial U.S. Approval: 1998RECENT MAJOR CHANGESIndications and Usage (1) 1/2023Dosage and Administration (2.1, 2.2, 2.3) 1/2023INDICATIONS AND USAGEAdultsSildenafil for oral suspension is a phosphodiesterase-5 (PDE-5) inhibitor indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. (1) (1)DOSAGE AND ADMINISTRATIONAdults: 20 mg three times a day Dose may be increased based on symptoms and tolerability. (2.1)DOSAGE FORMS AND STRENGTHSFor oral suspension: 10 mg/mL (when reconstituted) (3)CONTRAINDICATIONSWARNINGS AND PRECAUTIONSVasodilation effects may be more common in patients with hypotension or on antihypertensive therapy. (5.4, 5.5)Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil for oral suspension may cause serious vaso-occlusive crises. (5.6)Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil) product. (7)See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Revised: 1/2024 Adults: 20 mg three times a day Dose may be increased based on symptoms and tolerability. Pulmonary hypertension (PH) secondary to sickle cell disease: Sildenafil for oral suspension may cause serious vaso-occlusive crises. 1 INDICATIONS AND USAGE AdultsSildenafil for Oral Suspension is indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil) product. 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Dosage in AdultsOral DosageThe recommended dosage of Sildenafil for Oral Suspension is 20 mg three times a day. [see Clinical Studies (14)].Pediatric use information is approved for Viatris Specialty LLC's, REVATIO (sildenafil) product. However, due to Viatris Specialty LLC's marketing exclusivity rights, this drug product is not labeled with that information.2.3 Reconstitution of the Powder for Oral SuspensionNote: Reconstitute the contents of the bottle with a total volume of 92 mL (60 mL followed by 32 mL).
What happens if I overdose?
have an eye problem called retinitis pigmentosa have ever had sudden loss of vision in one or both eyes, including an eye problem called non-arteritic anterior ischemic optic neuropathy (NAION) have ever had hearing problems such as ringing in the ears, dizziness, or loss of hearing have a deformed penis shape or Peyronie’s disease have any blood cell problems such as sickle cell anemia are pregnant or plan to become pregnant. It is not known if sildenafil for oral suspension will harm your unborn baby. Talk with your healthcare provider about the best way to feed your baby during treatment with sildenafil for oral suspension. Tell your healthcare provider about all of the medicines you or your child take, including prescription and overthe-counter medicines, vitamins, and herbal supplements. Sildenafil for oral suspension and certain other medicines may affect each other and can cause side effects.
Does sildenafil interact with other medicines (drug interactions)?
See “What is the most important information I should know about sildenafil for oral suspension?” Sildenafil for oral suspension contains sildenafil, which is the same medicine found in another medicine called VIAGRA®. Do not take VIAGRA or other PDE-5 inhibitors during treatment with sildenafil for oral suspension. Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure. Know the medicines you or your child take. Keep a list of your or your child’s medicines and show it to your healthcare provider and pharmacist when you get a new medicine.
5.3 Epistaxis
Take or give sildenafil for oral suspension exactly as your healthcare provider tells you. Your healthcare provider may change your or your child’s dose of sildenafil for oral suspension as needed. Do not change your dose or stop taking sildenafil for oral suspension without talking to your healthcare provider. Sildenafil for oral suspension may be prescribed to you as sildenafil oral suspension. Take your prescribed dose of sildenafil oral suspension 3 times a day. 3 DOSAGE FORMS AND STRENGTHS Sildenafil for Oral SuspensionWhite to off-white powders containing 1.60 g of sildenafil citrate (equivalent to 1.14 g of sildenafil) in a bottle for reconstitution.
